منابع مشابه
Blood flow boosts BMP signaling to keep vessels in shape
Bone morphogenic proteins (BMPs) and blood flow regulate vascular remodeling and homeostasis. In this issue, Baeyens et al. (2016. J. Cell Biol http://dx.doi.org/10.1083/jcb.201603106) show that blood flow sensitizes endothelial cells to BMP9 signaling by triggering Alk1/ENG complexing to suppress cell proliferation and to recruit mural cells, thereby establishing endothelial quiescence.
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Human vascular malformations cause disease as a result of changes in blood flow and vascular hemodynamic forces. Although the genetic mutations that underlie the formation of many human vascular malformations are known, the extent to which abnormal blood flow can subsequently influence the vascular genetic program and natural history is not. Loss of the SH2 domain-containing leukocyte protein o...
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This excellent monograph by Phillippe Sengel brings together an enormous body of data on the embryonic development of the skin in mammals, birds, and reptiles, and most of the information available on the many chemical factors and tissue interactions which produce these changes. The book is divided into four sections. The first describes the histogenesis of developing skin visible with the ligh...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2017
ISSN: 0261-4189,1460-2075
DOI: 10.15252/embj.201797764